Anyone paying attention to these editorials knows we are passionate supporters of the Waisman Center, especially of the life-changing research into neurodegenerative diseases and causes of developmental disabilities done there.
Genetic counseling students learn to serve patients in ever-changing field
Many expected the Human Genome Project to cause a revolution far beyond the field of genetics — into economics and culture — and thought the 13-year, $3 billion international research endeavor would allow us to understand and control viruses, identify the root causes of cancers, advance forensics, create better crops and update anthropology tools to get a better view of our evolutionary path.
Samuel P Gubbels, MD
Title: Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreER(T2)/tdTomato-reporter mice Legend: Left image: Cochlea from an adult nestin-CreERT2/tdTomato-reporter mouse 56 days post tamoxifen injection. Low power macroscopic imaging …
Jan S. Greenberg, PhD
Title: The Relative Divorce Risk in Parents of a Child with Developmental Disabilities Legend: Left image: The Kaplan-Meier survival analysis with parents of a child with developmental disabilities (n=190) compared to parents of children without any …
Motherhood and mental health: Exploring the links between anxiety, depression and fragile X premutations
Women who have a child with fragile X syndrome (FXS) and are themselves carriers of a “premutation” in the gene linked to FXS are at an increased risk of developing depression and certain kinds of anxiety disorders over time, according to a recent study by researchers at the Waisman Center and the University of South Carolina.
Timothy M. Gomez, PhD
Legend: Top: A-B. 3D rendering of structured illumination microscopy (SIM) images of a human forebrain neuron growth cone triple-labeled for F-actin (red), ßIII tubulin (blue) and ADAM17 (green). A view of the apical surface (A) shows …
H. Hill Goldsmith, PhD
Legend: Left image: Children chronically at-risk for sensory processing disorders are more likely to have lower birthweight, lower gestational age, less sootheable and more fearful temperaments as toddlers. Right image: Severity of Age 4 sensory related …
David Gamm, MD, PhD
Title: Pharmacological modulation of photoreceptor outer segment degradation in Best disease patient-derived hiPSC-RPE Legend: (a) Representative western blot analysis comparing the amount of the POS protein RHO in untreated and VPA-treated (500 µmol/l) BD hiPSC-RPE at …
Peter Ferrazzano, MD
Title: Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury. Legend: P9 and P30 mice were exposed to unilateral hypoxia-ischemia and treated with minocycline or vehicle. A, B. Double immunohistological staining …
UW eye researchers publish second study of stem cells and blinding eye disease
A team of eye researchers at the University of Wisconsin-Madison have used a custom stem cell model of a rare but blinding eye disease to test whether a commonly used drug might offer hope for treatment.