Legend: Left panel: General patterns of [11C]PiB binding in participants with Down syndrome (DS). PiB binds to amyloid-β plaques, a neuropathological hallmark of Alzheimer’s disease (AD). The top row shows nonspecific white matter binding. The …
Evjue Foundation awards grants to Waisman Center Clinics and Discovery Garden
Two Waisman Center programs will benefit from The Evjue Foundation grants. The Waisman Center Clinics are the recipient of $11,500 to enhance exam rooms to minimize light and sound issues to better serve individuals with …
Expert: Editing stem cell genes will “revolutionize” biomedical research
Applying a dramatically improved method for “editing” genes to human stem cells, University of Wisconsin-Madison neuroscientist and Waisman Center investigator Su-Chun Zhang has shown a new way to silence genes in stem cells and their progeny at any stage of development.
Qiang Chang, PhD
Title: Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis Legend: Representative images (left) of adult neural progenitor cells (aNPCs) isolated from wild type (WT) and Mecp2S421A;S424A/y hippocampus with BrdU pulse labeling, followed by immunocytochemistry analysis. (middle) Representative …
Pelin Cengiz, MD
Title: Up-regulation of NHE1 protein expression in reactive hippocampal astrocytes Legend: A.Expression of NHE1 protein in hippocampal astrocytes. Immunofluorescence signals of NHE1 and GFAP were shown under normoxia control or OGD (2 h) plus 0 …
Ninth annual Fashion Show for All Abilities recap
Between wardrobe fittings, hours of coaching, makeup artists, and the moment that first shoe hits the runway, Chantel Brown watched her dream become a reality. Friday, May 29, 2015 marked the ninth annual Fashion Show for All Abilities where 73 models strut their stuff for this community awareness event.
Kindness in the classroom
What if teaching young children compassion and kindness made them better students as well as better people? Researchers with the UW’s Center for Investigating Healthy Minds at the Waisman Center recently tested that hypothesis with preschool students in the Madison Metropolitan School District, after years of work developing a curriculum designed to help children develop both kindness and self-regulation skills.
Ruth Munz receives Excellence in Early Education Award
Ruth Munz, a university associate in the Waisman Early Childhood Program, received the Excellence in Early Education Award last month after nomination from her co-workers. She was honored at Jazzin, the annual fundraiser for campus childcare and acknowledgement of exceptional early education teachers and leaders on campus.
Anita Bhattacharyya, PhD
Title: iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth Legend: Left panel: Skin cells from individuals with fragile X syndrome (FXS) can be reprogrammed into induced pluripotent stem cells (iPSCs) that …
Fragile X proteins involved in proper neuron development
Fragile X syndrome is the most common inherited intellectual disability and the greatest single genetic contributor to autism. Unlocking the mechanisms behind fragile X could make important revelations about the brain.