A fruit fly model of a rare, neurodegenerative disease is helping researchers trace the series of steps that lead to neuronal cell death. Damage to astrocytes – star-shaped cells found in the brain and spinal cord – is found in many neurodegenerative conditions, but it’s been unclear exactly what role astrocyte dysfunction plays in the development of disease.
Thoughts of Gratitude: David Busta
As basketball season gathers steam (go Badgers!), one small town in northern Wisconsin will be buzzing with excitement about a different basketball tournament on the Saturday after Thanksgiving.
Jeffrey Johnson, PhD
Title: Increasing Nrf2 activity in astrocytes confers protection to Nrf2 knockout neurons Legend: Nrf2 KO cultures were traduced with 50 MOI adenovirus-Nrf2-GFP or adenovirus-GFP 48 hours prior to H2O2 treatment. Cultures were immunohistochemically analyzed following treatment with 50 µM …
Waisman Center partners on new multi-site NIH initiative to find Alzheimer’s biomarkers in Down syndrome
Brad Christian, PhD, Waisman investigator and associate professor of medical physics and psychiatry, is part of a new National Institutes of Health initiative to identify biomarkers and track the progression of Alzheimer’s in people with Down syndrome.
Holiday cards for autism
Giizhik Klawiter has autism and began drawing at six years old as a therapeutic outlet. For the last six years, Giizhik and his brother Mino have designed holiday greeting cards and sold them in their hometown of Hayward, Wisconsin with the help of their mother, Pam Miller.
Searching for associations: New Waisman investigator studies child behavior disorders and the genetics and environment behind them
James Li’s drive to research, understand and develop effective interventions for childhood behavioral disorders, such as attention deficit hyperactivity disorder (ADHD), was sparked in the hallways of a juvenile justice center in Baltimore.
Ed Hubbard, PhD
Title: Perceptual Ratio Processing Predicts Fractions Skills Legend: (Lay): College students were asked to decide which of two ratios were larger (examples in a-d) that were presented for 1.5 seconds. We show that people who …
Derek Hei, PhD
Title: iPSC derived Optic Vesicles (OVs)/Neural Retinal Progenitors (NRPs) – Production, Characterization and Cryopreservation Legend: 1) Representative pictures of selected OVs derived from iPSCs grown on E8/Matrigel. iPSCs, cultured on E8/Matrigel, mTeSR1/Matrigel, and E8/vitronectin, were …
Divorce rate doesn’t go up as families of children with disabilities grow
Couples raising a child with developmental disabilities do not face a higher risk of divorce if they have larger families, according to a new study by researchers from the Waisman Center at the University of Wisconsin-Madison.
Sigan Hartley, PhD
Title: Support Needs of Fathers and Mothers of Children and Adolescents with Autism Spectrum Disorder Legend: Left, top image: The most support needs most frequently rated as both important and unmet for both mothers and …