Not so many years ago, people with Down syndrome rarely survived to middle age. Many died young due to heart problems associated with the congenital condition.
Today, advances in treatment have allowed them to live longer, healthier lives.
Down syndrome
Bradley T Christian, PhD – Slide of the Week
Individuals with Down syndrome (DS) are at increased risk of developing Alzheimer’s disease (AD) and show the earliest signs of amyloid-β (Aβ) deposition in the striatum. The metric for tracking Aβ burden using PET radiotracers frequently uses average standard uptake value ratios (SUVr) in signature regions of the brain specific to Aβ deposition.
New funding for Down syndrome research and biobank
The Waisman Center is one of 25 recipients to receive funding through a National Institutes of Health (NIH) grant that focuses on advancing research on Down syndrome. The grant is part of the NIH Investigation …
Waisman’s stem cell research into Down syndrome gives family hope
It’s not a cure for Down syndrome that Dave Witte and Cristina Delgadillo want for their 5-year-old daughter. “Olivia is our daughter and we love her, and we love her because of who she is. …
Bradley Christian, PhD – Slide of the Week
Trisomy 21 (Down syndrome; DS) leads to an overproduction of amyloid precursor protein and an increased risk for early Alzheimer’s disease. A study of the natural history of AD-related neuropathology is ongoing to gain an understanding of the distribution and time course of b-amyloid and tau burden in the brains of adults with DS.
Studying Alzheimer’s disease in individuals with Down syndrome
About once every year and a half, Erin Harvey takes time off of her job as a teacher’s aide and along with her mom, Nancy, makes a two and a half hour drive from her …
Anita Bhattacharyya, PhD – Slide of the Week
Neuropathology of the Down syndrome cerebral cortex includes fewer interneurons in upper cortical layers.
Houri K. Vorperian, PhD – Slide of the Week
A single-word identification test was used to study speech production in children and adults with Down syndrome (DS) to determine the developmental pattern of speech intelligibility with an emphasis on vowels.
Audra Sterling, PhD – Slide of the Week
This study compared gesture use in young children with DS and TD as well as how mothers respond to child gestures based on child age and diagnosis.
Down Syndrome Clinic helps Jackie Cleveland keep dancing
Brown eyes afire and colorful skirt awhirl, Jackie Cleveland has been dancing since she could walk.
Now in sixth-grade, Jackie, who has Down syndrome, performs at Native American pow wows across the country, dancing traditional Ho-Chunk dances with style and unabashed joy.