A new study of children with cerebral palsy could help ease the speech and language challenges many of these children face as they get older.
Krishanu Saha, PhD – Slide of the Week
We present and characterize a robust method for rapid, scarless introduction or correction of disease-associated variants in hPSCs using CRISPR/Cas9. Utilizing non-integrated plasmid vectors that express a puromycin N-acetyl-transferase (PAC) gene, whose expression and translation is linked to that of Cas9, we transiently select for cells based on their early levels of Cas9 protein.
Jenny Saffran, PhD – Slide of the Week
Children use the presence of familiar objects with known names to identify the correct referents of novel words. In natural environments, objects vary widely in salience. The presence of familiar objects may sometimes hinder rather than help word learning.
‘Drawn to Art’ features a unique partnership
The Wisconsin State Journal highlights how we are partnering with the Chazen Museum of Art to highlight beautiful pieces from our Harvey A. Stevens International Collection of Art by People with Developmental Disabilities.
Karl Rosengren, PhD – Slide of the Week
Although folding a piece of paper might seem simple for adults, it requires a complex integration of skills that might be difficult for children.
UW-Madison biomanufacturer offers essential gene-transfer capacity
Adeno-associated virus (AAV) is used to insert replacement genes, and its role in genetic therapy trials is expanding quickly, says Carl Ross, managing director of Waisman Biomanufacturing. The AAV production reflects the Waisman lab’s growing importance in the biopharma business, as it’s the only facility on campus meeting FDA “good manufacturing practices” rules for large-scale manufacturing of biological therapies.
Scientists just beginning to understand the unique health needs of adults with autism
In the 1990s, the prevalence of autism spectrum disorder (ASD) among children rose sharply. These children are now entering adulthood, yet physicians and scientists know very little about the health outcomes they might face. Most studies of health have focused on children and adolescents.
Paul Rathouz, PhD – Slide of the Week
Early diagnosis of speech disorders in children with cerebral palsy (CP) is of critical importance. A key problem is differentiating those with borderline or mild speech motor deficits from those who are within an age appropriate range of variability.
New CDC report finds increasing prevalence of autism in school-age children
An estimated 1 in 59 school-aged children have been identified with autism spectrum disorder (ASD) according to a new report by the Centers for Disease Control (CDC). The latest estimate is higher than the prevalence in the CDC’s 2016 report (1 in 68 children).
Seth Pollak, PhD – Slide of the Week
Individuals who have experienced chronic and high levels of stress during their childhoods are at increased risk for a wide range of behavioral problems, yet the neurobiological mechanisms underlying this association are poorly understood.