Title: iPSC derived Optic Vesicles (OVs)/Neural Retinal Progenitors (NRPs) – Production, Characterization and Cryopreservation Legend: 1) Representative pictures of selected OVs derived from iPSCs grown on E8/Matrigel. iPSCs, cultured on E8/Matrigel, mTeSR1/Matrigel, and E8/vitronectin, were …
Slide of the Week
Sigan Hartley, PhD
Title: Support Needs of Fathers and Mothers of Children and Adolescents with Autism Spectrum Disorder Legend: Left, top image: The most support needs most frequently rated as both important and unmet for both mothers and …
Samuel P Gubbels, MD
Title: Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreER(T2)/tdTomato-reporter mice Legend: Left image: Cochlea from an adult nestin-CreERT2/tdTomato-reporter mouse 56 days post tamoxifen injection. Low power macroscopic imaging …
Jan S. Greenberg, PhD
Title: The Relative Divorce Risk in Parents of a Child with Developmental Disabilities Legend: Left image: The Kaplan-Meier survival analysis with parents of a child with developmental disabilities (n=190) compared to parents of children without any …
Timothy M. Gomez, PhD
Legend: Top: A-B. 3D rendering of structured illumination microscopy (SIM) images of a human forebrain neuron growth cone triple-labeled for F-actin (red), ßIII tubulin (blue) and ADAM17 (green). A view of the apical surface (A) shows …
H. Hill Goldsmith, PhD
Legend: Left image: Children chronically at-risk for sensory processing disorders are more likely to have lower birthweight, lower gestational age, less sootheable and more fearful temperaments as toddlers. Right image: Severity of Age 4 sensory related …
David Gamm, MD, PhD
Title: Pharmacological modulation of photoreceptor outer segment degradation in Best disease patient-derived hiPSC-RPE Legend: (a) Representative western blot analysis comparing the amount of the POS protein RHO in untreated and VPA-treated (500 µmol/l) BD hiPSC-RPE at …
Peter Ferrazzano, MD
Title: Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury. Legend: P9 and P30 mice were exposed to unilateral hypoxia-ischemia and treated with minocycline or vehicle. A, B. Double immunohistological staining …
Susan Ellis Weismer, PhD
Legend: Latent growth curve modeling of longitudinal data (age 2-5 years) for 129 young children with ASD revealed four severity trajectory classes based on calibrated severity scores from the Autism Diagnostic Observation Schedule (ADOS): Persistent …
Jan Edwards, PhD
Legend: Fig. 1. The tokens of the determiner the for the three item types. Note the canonical formant transitions for the facilitating tokens and the steady formant values in the neutral token. Fig. 2. Proportion …