Basal forebrain cholinergic neurons (BFCNs) are integral to learning, attention, and memory, and are prone to degeneration in Down syndrome (DS), Alzheimer’s disease, and other neurodegenerative diseases.
Slide of the Week
Barbara B. Bendlin, PhD – Slide of the Week
The gut microbiome is a potentially modifiable risk factor for Alzheimer’s disease (AD); however, understanding of its composition and function regarding AD pathology is limited.
Erik W. Dent, PhD – Slide of the Week
Neurite initiation from newly born neurons is a critical step in neuronal differentiation and migration.
Jenny Saffran, PhD – Slide of the Week
How do infants become word meaning experts? This registered report investigated the structure of infants’ early lexical representations by manipulating the typicality of exemplars from familiar animal categories.
Kristin Shutts, PhD – Slide of the Week
Disciplines across the social and behavioral sciences have documented the critical role of early peer connections in children’s development, yet mechanisms facilitating these connections have not been tested in controlled laboratory settings.
Xinyu Zhao, PhD – Slide of the Week
The human genome has many short tandem repeats, yet the normal functions of these repeats are unclear.
Donna Werling, PhD – Slide of the Week
Title: Use of the new human telomere-to-telomere genomic reference improves variant calling and phasing in regions flanking developmental disorder-associated copy number variants Legend: Genotyping and switch error rates spike in areas flanking CNV disorder associated regions. …
Marsha R. Mailick, PhD – Slide of the Week
Parenting a child with a developmental disability can be a profound source of stress, particularly for mothers.
Daifeng Wang, PhD – Slide of the Week
Cellular processes like development, differentiation, and disease progression are highly complex and dynamic (e.g., gene expression).
Masatoshi Suzuki, DVM, PhD – Slide of the Week
Although ALS has historically been characterized as a motor neuron disease, there is evidence that motor neurons degenerate in a retrograde manner, beginning in the periphery at the neuromuscular junctions (NMJs) and skeletal muscle.