The hallmarks of Alexander disease, aggregation of misfolded GFAP proteins and dysregulation of brain cells called astrocytes, may be stopped and reversed in rodent models with the inactivation of the transcription factor STAT3.
Research
Understanding autism from the minute to the masses: Autism research at the Waisman Center
Autism spectrum disorder (ASD) is an intricate and complicated diagnosis. The spectrum of presentations and severity is as expansive as the theorized causes. Autism’s complexity and breadth of impacts on a person’s life means that it has a multitude of facets to investigate.
Tiny antennas open door to injectable electronics for brain monitoring
Sensory responses in autistic children are linked to a small under-explored region tucked deep down in the brain called the brainstem
The same external sensory stimulus – a flashing light, a hug, or hearing one’s name – can provoke a different reaction in every person.
In the lab where sign language advances science: A spotlight on Phu Duong
Epigenetics – the study of how environment can change and affect how genes function – was a new field for Phu Duong, PhD.
Women’s History Month: Celebrating the women of Waisman | Infographic
For Women’s History Month we are celebrating all of the women of Waisman who are advancing knowledge of intellectual and developmental disabilities and providing cutting-edge clinical care.
Hope for failing eyes
Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new UW study, completing a “handshake” that may show the cells are ready for trials in humans with degenerative eye disorders.
From brain stimulation to speech and language interventions, Waisman researchers are making strides to better understand and treat individuals with cerebral palsy
More than 10,000 children are born each year with cerebral palsy (CP) making it the most common motor disability in childhood.
Resilience doesn’t equate to positive outcomes for individuals who have experienced early childhood maltreatment
Early childhood maltreatment can have long lasting effects that follow a person into adulthood.
Alexander disease: A lifetime’s work in the hope of saving lives
Messing wanted to study if the overexpression of GFAP resulted in a certain reactive response in the brain.