Legend: Top: A-B. 3D rendering of structured illumination microscopy (SIM) images of a human forebrain neuron growth cone triple-labeled for F-actin (red), ßIII tubulin (blue) and ADAM17 (green). A view of the apical surface (A) shows …
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H. Hill Goldsmith, PhD
Legend: Left image: Children chronically at-risk for sensory processing disorders are more likely to have lower birthweight, lower gestational age, less sootheable and more fearful temperaments as toddlers. Right image: Severity of Age 4 sensory related …
David Gamm, MD, PhD
Title: Pharmacological modulation of photoreceptor outer segment degradation in Best disease patient-derived hiPSC-RPE Legend: (a) Representative western blot analysis comparing the amount of the POS protein RHO in untreated and VPA-treated (500 µmol/l) BD hiPSC-RPE at …
Peter Ferrazzano, MD
Title: Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury. Legend: P9 and P30 mice were exposed to unilateral hypoxia-ischemia and treated with minocycline or vehicle. A, B. Double immunohistological staining …
UW eye researchers publish second study of stem cells and blinding eye disease
A team of eye researchers at the University of Wisconsin-Madison have used a custom stem cell model of a rare but blinding eye disease to test whether a commonly used drug might offer hope for treatment.
Susan Ellis Weismer, PhD
Legend: Latent growth curve modeling of longitudinal data (age 2-5 years) for 129 young children with ASD revealed four severity trajectory classes based on calibrated severity scores from the Autism Diagnostic Observation Schedule (ADOS): Persistent …
Jan Edwards, PhD
Legend: Fig. 1. The tokens of the determiner the for the three item types. Note the canonical formant transitions for the facilitating tokens and the steady formant values in the neutral token. Fig. 2. Proportion …
Maureen S. Durkin, PhD
Citation: Inter-pregnancy intervals and the risk of autism spectrum disorder: results of a population-based study. Durkin MS, DuBois LA, Maenner MJ, Journal of Autism and Developmental Disorders, 2015; 45(7): 2056-66. Abstract: Recent studies have reported …
Richard Davidson, PhD
Title: Amygdala and hippocampal volume is reduced in children exposed to different forms of adversity Legend: Volumetric comparisons for the left amygdala (A) and left (B) and right (C) hippocampus. For each graph, standardized residuals controlling …
Zhang’s startup looks to give hope to patients with neurological disorders
In his 19-year career at UW–Madison, Dr. Su-Chun Zhang has transformed the field of stem cell research. The renowned neuroscientist was the first in the world to isolate neural stem cells from embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), a landmark discovery he patented with the help of the Wisconsin Alumni Research Foundation (WARF) in 2001.